Probiotics with Prebiotics - 60 Capsules

You've been bloating every day. You've tried a probiotic. Nothing changed. The problem probably isn't probiotics, it's which ones, and whether they survived long enough to matter.

Most probiotic supplements fail at the most basic level: the bacteria don't survive the journey from the capsule to your intestine. Stomach acid, bile salts, and digestive enzymes wipe out conventional strains before they can do anything. What gets absorbed, if anything, is a fraction of what's on the label. The second failure is simpler. Single-strain or low-diversity formulas cannot restore a depleted gut ecosystem. Your microbiome has hundreds of species operating across distinct regions of your digestive tract. A product with two or three strains doesn't cover it.

iThrive Probiotics with Prebiotics is built around two solutions to these two problems.

Survivability: two spore-forming strains (LactoSpore® and DE111®) that are inherently acid-resistant, plus delayed-release capsule technology that protects conventional strains through the stomach and releases them in the intestine where they belong.

Diversity: 12 strains across 5 genera such as Lactobacillus, Bifidobacterium, Bacillus, Streptococcus, and Saccharomyces, covering the small intestine, large intestine, immune interface, and gut-barrier function simultaneously.

And because probiotics without the right food don't colonize effectively, two precision prebiotics namely Livaux® organic FOS from gold kiwi fruit and organic pomegranate peel, provide targeted nourishment for the bacterial species that matter most.

What most probiotics miss and why it matters

12 strains. Each one in here for a reason.

The strains are grouped by function and location in your digestive tract — because a well-formulated probiotic covers the full length of the gut, not just one part of it.

Spore-forming strains are survival specialists

These two strains form protective spores that survive stomach acid, bile salts, and digestive enzymes intact. They don't need refrigeration and they arrive in the intestine fully active.

Lactobacillus strains for small intestine & immune interface

Lactobacillus species are the primary colonizers of the small intestine. This group covers the three most clinically researched functions: antibiotic recovery, immune modulation, and intestinal wall adhesion.

Bifidobacterium strains for large intestine & metabolic health

Bifidobacteria dominate the large intestine and are the primary bacteria lost with age, antibiotics, and processed food diets. This group targets bowel transit, gut barrier integrity, and metabolic function.

Specialized strains for targeted functions

The two prebiotics and why generic FOS isn't enough

Most probiotic formulas include generic FOS (fructooligosaccharides) as a prebiotic. Generic FOS feeds a broad range of bacteria — which sounds good, but in practice feeds the problematic ones too, often causing the bloating people are trying to fix.

iThrive Probiotics uses two precision prebiotics instead:

Livaux® Organic FOS (from gold kiwi fruit) — unlike generic FOS, Livaux® has been shown to specifically promote the growth of Faecalibacterium prausnitzii, one of the most important keystone bacteria in a healthy gut. F. prausnitzii is a keystone species linked to gut microbiome balance. Livaux® feeds this bacteria specifically without feeding problematic species.

Organic Pomegranate Peel Powder (Punica granatum) — rich in ellagitannin polyphenols that selectively feed Akkermansia muciniphila, the bacteria responsible for maintaining the mucus layer lining your gut wall. Akkermansia plays a role in maintaining the gut's mucus lining. Pomegranate peel supports this bacteria while providing antioxidant protection to the gut lining.

What iThrive Probiotics with Prebiotics may support

Digestive comfort such as bloating, gas, irregular bowel movements

• LactoSpore® and NCFM® may support relief from bloating and abdominal discomfort
• HN019™ is clinically studied for improving gut transit time and bowel movement regularity
• Delayed-release capsule technology ensures strains reach the large intestine where digestive symptoms originate

Post-antibiotic gut recovery

• LGG® is the most researched strain globally for antibiotic-associated diarrhea prevention
• Lynside® Saccharomyces boulardii is naturally antibiotic-resistant and continues working even during antibiotic courses
• LPC-37® supports recovery of the microbiota diversity wiped out by antibiotic treatment

Immune function

• Approximately 70% of immune cells are located in the gut lining, and a healthy microbiome plays a significant role in immune function
• BI-04® may support reduction of upper respiratory tract infection risk
• Spore-forming strains crowd out pathogenic bacteria and create conditions for immune-supporting species to thrive

Skin and brain fog linked to gut dysbiosis

• A balanced gut microbiome is increasingly linked to skin and cognitive wellness
• Restoring microbiome diversity with broad-spectrum strains addresses the root cause rather than the symptom

Metabolic and hormonal concerns

• B420® may support gut barrier integrity, which is associated with balanced metabolic and inflammatory markers
• Livaux® supports F. prausnitzii which is a keystone species consistently depleted in people with metabolic conditions.

12 strains, 2 prebiotics. Nothing added to make manufacturing easier.

No magnesium stearate. No silicon dioxide. No artificial colours. No preservatives. No synthetic fillers. Gluten-free, soy-free, dairy-free, non-GMO.

The capsule shell is 100% HPMC, vegetarian and clean. Delayed-release technology is built into the capsule itself, not achieved with synthetic coatings.

Spore-forming strains (LactoSpore® and DE111®) are shelf-stable without refrigeration. Conventional strains are protected by delayed-release capsule technology and arrive live in the intestine.

GMP certified. Third-party lab tested. 55 Billion CFUs clinically relevant potency, not inflated numbers for marketing purposes.

How to use

Take 2 capsules daily with/before food. If you experience any initial digestive sensitivity, starting with 1 capsule and building to 2 over a week is perfectly acceptable.

Can be taken alongside: iThrive Zinc Defense (space 1–2 hours apart), iThrive Active B-Complex (B vitamins support gut lining integrity), and iThrive Detox Binder if on an antimicrobial or anti-fungal protocol, the binder supports clearance of die-off toxins while probiotics restore the microbiome.

Note on timing with antibiotics: Saccharomyces boulardii (Lynside®) is naturally antibiotic-resistant and can be taken simultaneously with antibiotic courses. Other strains should be spaced 2 hours away from the antibiotic dose.

Practitioner's Note

"The question we ask first with any probiotic formula isn't which strains, it's how many of them are actually reaching alive. Most conventional strains are dead before they reach the intestine. That's not a marketing problem, it's a delivery problem. The spore-formers in this formula namely LactoSpore® and DE111® solve it structurally. They don't need the capsule to protect them because they protect themselves. The delayed-release capsule is there for the conventional strains. On the prebiotic side, the decision to use Livaux® instead of generic FOS came down to specificity. Generic FOS feeds broadly, including species you don't want to overgrow. Livaux® has evidence for selectively promoting F. prausnitzii, which is the strain most consistently absent in people presenting with gut symptoms. Pomegranate peel does the same for Akkermansia, the bacteria maintaining your gut's mucus barrier. These weren't interchangeable choices."

Suyash Bhandari
In-House Scientist & Head of Formulations, iThrive Essentials

Essentials are not generic supplements sold alongside the program. They are the protocol.