Active B-Complex - 90 Capsules

You take B vitamins every day. You still feel tired.

The reason is almost always the same the B vitamins in most supplements are in synthetic, inactive forms that your body has to convert before it can use them. Folic acid has to become 5-MTHF. Cyanocobalamin has to become methylcobalamin. Pyridoxine has to become P5P. If anything in those conversion chains is suboptimal due to chronic stress, gut inflammation, a common genetic variant, the conversion doesn’t happen fully. And you absorb a fraction of what the label says you’re getting.

iThrive Active B-Complex skips the conversion step entirely. Every B vitamin in this formula is already in its active, metabolically ready form. What goes in is what your cells use.

Most B-complex supplements use the cheap forms. Here’s the difference:

Note on Quatrefolic®: This is not generic 5-MTHF. Quatrefolic® is a patented (6S)-5-methyltetrahydrofolate glucosamine salt from Gnosis by Lesaffre, the same high-purity active folate used in clinical prenatal and MTHFR protocols globally. It is the gold standard for bioavailable folate supplementation.

Why this matters especially if you have PCOS or are planning conception:

The MTHFR gene variant carried by approximately 10 to 15 percent of people  impairs the enzyme that converts folic acid into the active folate your cells need. Women with PCOS have a higher prevalence of this variant. This is why functional nutritionists who work with PCOS routinely move patients away from folic acid and onto active folate like Quatrefolic®.

iThrive Active B-Complex includes 300mcg of Quatrefolic® active folate per capsule (100% RDA) alongside 100mg of Myo-Inositol, which supports insulin sensitivity and ovarian function in PCOS, and 100mg of Phosphatidylcholine from sunflower lecithin (not soy), which supports cell membrane integrity and liver function.

No other Indian B-complex provides all three of these in one capsule.

What iThrive Active B-Complex may support:

• Energy metabolism — all 8 B vitamins participate in converting food to cellular energy (ATP)

• Mental clarity and focus — B vitamins are cofactors in neurotransmitter synthesis; deficiency is consistently linked to brain fog

• Stress response — B5, B6, and B12 are essential for the adrenal stress response; depleted rapidly under chronic stress

• Hormonal balance and PCOS — active folate supports methylation, Myo-Inositol aids insulin sensitivity and ovarian function

• Preconception and pregnancy — Quatrefolic® active folate is the clinically recommended form before and during conception

• Liver and cell membrane health — Phosphatidylcholine from sunflower lecithin supports liver fat metabolism and cell membrane integrity

• Mood balance — B6, B9, and B12 are required for serotonin, dopamine, and norepinephrine synthesis

• Hair, skin, and nails — D-Biotin (B7) supports keratin infrastructure; the active form bypasses absorption issues common with generic biotin

The formula is built around what’s in it and what isn’t.

No magnesium stearate. No silicon dioxide. No titanium dioxide. No artificial colours. No synthetic preservatives. No folic acid (the synthetic, inactive form). No cyanocobalamin (the cheap B12 form most brands use).

Preserved naturally with rosemary extract used to protect the active B vitamins from oxidation during shelf life, without introducing synthetic antioxidants.

The capsule shell is 100% HPMC vegetarian, clean, free from gelatin. Sunflower lecithin, not soy lecithin, so it’s suitable for anyone avoiding soy.

How to use

Take 1 capsule after each meal, up to 3 times daily or as suggested by your healthcare practitioner. Each capsule delivers 100% RDA of every B vitamin in its active form.

Practical note: Starting with 1 capsule per day and increasing gradually is advisable for those new to active B vitamins, as higher doses can occasionally cause mild initial responses (vivid dreams, warm skin flush from niacin). These settle within a few days for most people.

Can be taken alongside: iThrive Magnesium Bisglycinate (magnesium supports B vitamin activation), iThrive Vitamin D3+K2 (D3 metabolism requires B vitamins), and iThrive Marine Omega-3 (B12 and omega-3 work synergistically for brain and cardiovascular health).

Practitioner’s Note

“The two decisions that distinguish this formula from most B-complex supplements on the market are the choice of folate and the addition of Myo-Inositol. On folate, we use Quatrefolic®, the patented (6S)-5-methyltetrahydrofolate from Gnosis. This is not the same as generic L-methylfolate. Quatrefolic® has superior stability, documented bioavailability data, and is specifically the form used in clinical research with MTHFR populations and preconception protocols. On Myo-Inositol this is typically sold as a standalone PCOS supplement at ₹1,000+ per bottle. Combining it with active B vitamins in a single capsule reflects how practitioners actually use these nutrients together in clinical protocols not in isolation. The Phosphatidylcholine from sunflower lecithin completes the picture: it supports cell membrane synthesis and liver fat metabolism, functions that are often overlooked in standard B-complex formulations.”  Suyash Bhandari In-House Scientist & Head of Formulations, iThrive Essentials