9AM - 5 PM
iThrive Healing and Beyond in collaboration with Precision Analytical Labs USA Dutch Plus Hormone Panel DUTCH Complete
The The DUTCH Plus® is an upgraded version of the DUTCH Complete ™ panel.
The DUTCH Plus® takes hormone testing to a whole new level. In addition to sex hormones and their metabolites, the DUTCH CompleteTM looks at the overall diurnal pattern of free cortisol, and the total and distribution of cortisol metabolites.
The DUTCH Plus® adds the Cortisol Awakening Response (CAR) to bring another important piece of the HPA-axis into focus.
Sample required : SALIVA & URINE
What is the Cortisol Awakening Response and how do we test for it?
When we open our eyes upon waking, cortisol levels naturally begin to rise by an average of 50%. 30 minutes after waking, cortisol levels will still show this sharp increase. By 60 minutes after waking, cortisol levels have peaked and begin to decline. Measuring this rise and fall of cortisol levels at waking can be used as a “mini stress test”. Research shows that the size of this increase correlates with HPA Axis function, even if the sample measurements are all within range. A quick saturation of saliva swabs upon waking, and at 30 and 60 minutes after waking, provide what is required to assess a patient’s Cortisol Awakening Response.
What’s Included in the DUTCH Plus® ?
The DUTCH Plus® uses four dried urine samples and five saliva samples. These samples are collected over the course of one day, from waking to bed time. The DUTCH Plus® report includes: Metabolites of Estrogens (10, including E1, E2, E3, 2-OHE1, 4-OH-E1, 2-OH-E2, 4-OH-E2, 16-OH-E1, 2-methoxy-E1, 2-methoxy-E2) , Androgens (8, including Testosterone, DHT and DHEA-S), Progesterone (2), Cortisol (3), Melatonin (6OHMS), 8-OHdG, and OATs (9). The diurnal pattern of Free Cortisol and Cortisone are also provided, including the Cortisol Awakening Response.
What can the DUTCH Plus®tell us that the DUTCH Complete™ and other adrenal tests cannot?
Even though a patient may have “normal” free cortisol levels throughout the day, that doesn’t always mean everything is functioning properly. The graph below shows two good examples. A blunted or exaggerated CAR can appear, even when single samples return “normal” results. The HPA axis might not be appropriately responding when faced with a stressor, even when cortisol levels are fluctuating nicely throughout the day. The “stress” of waking allows us to test the HPA axis in a way that has been independently correlated to clinical outcomes and cannot be assessed by other cortisol tests on the market.
Some conditions that warrant testing are:
Dutch Plus Sample report :
Female :https://dutchtest.com/wp-content/uploads/2020/03/CAR-Only-Female-Sample-Report-Ref032620.pdf
Male : https://dutchtest.com/wp-content/uploads/2022/06/Sample-Report_DUTCH-Plus_Male_RevB1-062022.pdf
How is the test done?
Please note : Charges for shipping the sample to the Lab in Denmark are included in the test cost itself and you do not need to pay any extra charges.
Contact us:
Vendor: | iThrive Essentials |
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SKU: | DUP01 |